CAGRILINTIDE 5MG

Cagrilintide 5 mg — Long-Acting Amylin Analog for Metabolic & Appetite Research

Cagrilintide is a long-acting synthetic amylin analog investigated in metabolic and obesity-related research. Designed to mimic the activity of the endogenous hormone amylin, Cagrilintide has been studied for its effects on appetite regulation, gastric emptying, satiety signaling, and body-weight management pathways.

In preclinical and exploratory clinical research, Cagrilintide has demonstrated potential utility in studies involving caloric intake modulation, energy balance, and metabolic-response markers.

What It Is

• Class: Long-acting amylin receptor agonist
• Concept: Engineered to extend the biological activity of native amylin while improving stability and receptor interaction in research settings.
• Format: Research-grade synthetic peptide supplied as a lyophilized powder.

Proposed Mechanisms (Preclinical)

Appetite & Satiety Signaling

• Investigated for activation of amylin receptors involved in appetite suppression and satiety pathways.
• Studied for reduction of caloric intake and feeding behavior in obesity-related models.
• Explored for delayed gastric emptying effects contributing to prolonged fullness signaling.

Metabolic & Weight-Related Endpoints

• Animal studies have evaluated effects on body-weight trajectories and adiposity markers.
• Research interest includes glucose-regulation pathways, insulin sensitivity markers, and lipid metabolism.
• Exploratory human datasets have examined tolerability, appetite-related endpoints, and metabolic-profile modulation.

Combination Research Interest

• Cagrilintide has attracted research interest in combination protocols involving GLP-1 receptor agonists due to complementary mechanisms related to appetite regulation and energy balance.

Selected Research Highlights

• Obesity Models: Evaluated in diet-induced obesity models for effects on food intake, body composition, and metabolic markers.
• Human Studies: Early-phase clinical investigations have focused on tolerability, satiety response, and weight-related endpoints.
• Mechanistic Interest: Research suggests potential synergistic interactions between amylin analogs and incretin-based pathways.

Chemical & Handling Information

• Type: Synthetic long-acting amylin analog
• Appearance: White to off-white lyophilized powder
• Research Use: Intended strictly for laboratory and research applications

Specifications

• Peptide: Cagrilintide
• Amount: 5 mg per vial
• Form: Lyophilized powder
• Purity: ≥99% (HPLC); COA per lot available
• Packaging: Sealed vials suitable for standard laboratory handling

Storage & Stability

• Store lyophilized vials in a cool, dry place protected from light.
• For extended stability, refrigeration or freezing of the lyophilized peptide is recommended per laboratory SOPs.
• After reconstitution, store at 2–8 °C for short-term use.
• For long-term storage, aliquot and freeze at −20 °C or below; avoid repeated freeze–thaw cycles.