Melanotan 1 10MG

Melanotan II 10 mg — Melanocortin Receptor Peptide for Pigmentation & CNS Research

Melanotan II is a synthetic melanocortin receptor agonist peptide derived from the ?-melanocyte–stimulating hormone (?-MSH) family. In preclinical and exploratory human research, Melanotan II has been investigated for its effects on skin pigmentation pathways and central melanocortin signaling related to appetite, mood, and autonomic function.

What It Is

• Class: Melanocortin receptor agonist peptide
• Origin concept: Analog of ?-MSH with sequence modifications to enhance stability and receptor affinity.
• Research focus: Pigmentation biology, melanocortin systems in the CNS, and autonomic/neuroendocrine readouts.

Proposed Mechanisms (Preclinical)

Pigmentation & Melanocortin Receptors

• Acts at melanocortin receptors including MC1R on melanocytes.
• MC1R activation is linked to melanogenesis and changes in eumelanin production in pigmentation models.
• Used to study UV-response pathways, melanin production, and photobiology in vitro and in vivo.

CNS & Autonomic Pathways

• Melanocortin receptors (e.g., MC3R/MC4R) are expressed in central nervous system regions regulating appetite, energy balance, and autonomic output.
• Experimental work explores CNS-mediated effects on behavior, appetite, and autonomic markers.
• Interest in overlapping biology with other ?-MSH–derived peptides, including PT-141/Bremelanotide.

Selected Research Highlights

• Pigmentation Research: Melanotan II has been used as a reference melanocortin agonist in models of skin pigmentation, tanning response, and UV-protection pathways.
• CNS & Behavioral Models: Experimental studies examine melanocortin signaling in appetite, mood, and autonomic regulation.
• Melanocortin System Biology: Serves as a tool compound for mapping MC1R–MC4R receptor networks and downstream intracellular signaling (e.g., cAMP/PKA pathways).

Chemical & Handling Information

• Type: Synthetic melanocortin receptor agonist peptide
• Peptide family: ?-MSH–derived cyclic peptide analog
• Appearance: White to off-white lyophilized powder

Specifications

• Form: Lyophilized powder
• Purity: ?99% (HPLC); COA per lot available
• Packaging: Sealed vials suitable for standard laboratory handling

Storage & Stability

• Store lyophilized vials in a cool, dry place, protected from light.
• Refrigeration or freezing of the lyophilized peptide is recommended for extended stability, according to laboratory SOPs.
• After reconstitution, store at 2–8 °C for short-term use.
• For long-term storage, aliquot and freeze at ?20 °C or below; avoid repeated freeze–thaw cycles.