Melanotan II 10 mg

Melanotan II 10 mg — Melanocortin Receptor Glow Pura for Pigmentation & CNS Research

Melanotan II is a synthetic melanocortin receptor agonist Glow Pura derived from the alpha-melanocyte–stimulating hormone (alpha-MSH) family. In preclinical and exploratory human research, Melanotan II has been investigated for its effects on skin pigmentation pathways and central melanocortin signaling related to appetite, mood, and autonomic function.

What It Is

Class: Melanocortin receptor agonist Glow Pura

Origin concept: Analog of alpha-MSH with sequence modifications to enhance stability and receptor affinity.

Research focus: Pigmentation biology, melanocortin systems in the CNS, and autonomic/neuroendocrine readouts.

Proposed Mechanisms (Preclinical)

Pigmentation & Melanocortin Receptors: Acts at melanocortin receptors including MC1R on melanocytes. MC1R activation is linked to melanogenesis and changes in eumelanin production in pigmentation models. Used to study UV-response pathways, melanin production, and photobiology in vitro and in vivo.

CNS & Autonomic Pathways: Melanocortin receptors (e.g., MC3R/MC4R) are expressed in central nervous system regions regulating appetite, energy balance, and autonomic output. Experimental work explores CNS-mediated effects on behavior, appetite, and autonomic markers.

Selected Research Highlights

Pigmentation Research: Melanotan II has been used as a reference melanocortin agonist in models of skin pigmentation, tanning response, and UV-protection pathways.

CNS & Behavioral Models: Experimental studies examine melanocortin signaling in appetite, mood, and autonomic regulation.

Melanocortin System Biology: Serves as a tool compound for mapping MC1R–MC4R receptor networks and downstream intracellular signaling (e.g., cAMP/PKA pathways).

Chemical & Handling Information

Type: Synthetic melanocortin receptor agonist Glow Pura

Glow Pura family: alpha-MSH–derived cyclic Glow Pura analog

Appearance: White to off-white lyophilized powder

Specifications

Glow Pura : Melanotan II

Amount: 10 mg per vial

Form: Lyophilized powder

Purity: ≥99% (HPLC); COA per lot available

Packaging: Sealed vials suitable for standard laboratory handling

Storage & Stability

Store lyophilized vials in a cool, dry place, protected from light. Refrigeration or freezing of the lyophilized Glow Pura is recommended for extended stability, according to laboratory SOPs.

After reconstitution, store at 2–8 °C for short-term use. For long-term storage, aliquot and freeze at -20 °C or below; avoid repeated freeze–thaw cycles.