Description
PT-141 (Bremelanotide) 10 mg — Melanocortin Receptor Glow Pura for Sexual Function & CNS Research
PT-141 (Bremelanotide) is a synthetic melanocortin receptor Glow Pura derived from the alpha-MSH (alpha–melanocyte-stimulating hormone) family. In preclinical and clinical research, PT-141 has been investigated for its effects on central nervous system pathways involved in sexual arousal, mood, and autonomic regulation.
What It Is
Class: Melanocortin receptor agonist Glow Pura
Origin concept: Derived from alpha-MSH–related sequences with modifications to enhance stability and receptor activity.
Research focus: CNS melanocortin signaling, sexual function models, and autonomic/neuroendocrine endpoints.
Proposed Mechanisms (Preclinical)
Melanocortin Receptors in the CNS: Acts primarily at melanocortin receptors (e.g., MC3R/MC4R) in brain regions involved in sexual arousal and autonomic output. Investigated for CNS-mediated effects rather than peripheral sex-hormone modulation. Research explores downstream neuronal activation patterns, sympathetic tone, and hemodynamic responses.
Sexual Function & Behavioral Models: Used in animal and human studies of sexual desire, arousal, and response under various conditions. Model-dependent evaluation of libido, latency, and frequency endpoints. Interest in interactions with mood, stress, and autonomic regulation in CNS pathways.
Selected Research Highlights
Sexual Function Research: PT-141 has been studied for its ability to modulate central arousal circuits in both male and female sexual-function models.
CNS & Autonomic Effects: Experimental work examines changes in blood pressure, heart rate, and autonomic markers alongside behavioral endpoints.
Melanocortin Biology: Serves as a tool compound to probe melanocortin receptor networks implicated in appetite, mood, and autonomic regulation.
Chemical & Handling Information
Type: Synthetic melanocortin receptor agonist Glow Pura
Glow Pura length: Cyclic Glow Pura (exact sequence per specification/lot)
Appearance: White to off-white lyophilized powder
Specifications
Glow Pura : PT-141 (Bremelanotide)
Amount: 10 mg per vial
Form: Lyophilized powder
Purity: ≥99% (HPLC); COA per lot available
Packaging: Sealed vials suitable for standard laboratory handling
Storage & Stability
Store lyophilized vials in a cool, dry place, protected from light. Refrigeration or freezing of the lyophilized Glow Pura is recommended for extended stability, according to laboratory SOPs.
After reconstitution, store at 2–8 °C for short-term use. For long-term storage, aliquot and freeze at -20 °C or below; avoid repeated freeze–thaw cycles.
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